CHROMOSOME 7 DDC 7p12.2-p12.1 GENE VIEW DDC · 7p12.2-p12.1 7p13 7p11 rs1470750 — ~70,000 base pairs in the gene — ~14,000 uncommon variants · <1% of humans have them — ~1,000 common variants · >1% carry the alternate allele ALLELE STATE rs1470750 C / G · DDC · 7p12.2-p12.1 HOMOZYGOUS WILD TYPE (DOMINANT) 5′ 3′ C 5′ 3′ C HETEROZYGOUS 5′ 3′ C 5′ 3′ G HOMOZYGOUS ALTERNATE (RECESSIVE) 5′ 3′ G 5′ 3′ G C Cytosine — reference allele G Guanine — variant allele genetics.jdge.cc

rs1470750

Gene: DDC — Dopa Decarboxylase Chr 7:50508950 7p12.2-p12.1 Intron Variant
NCBI ↗ Research Rabbit ↗ GeneCards ↗ Open Targets ↗ gnomAD ↗ OMIM ↗ Varsome ↗ LOVD ↗

Population Frequencies12

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Total C 0.68155G 0.31845CC 0.479452CG/GC 0.40419GG 0.116358pop=24,820
African C 0.9226G 0.0774CC 0.853544CG/GC 0.138179GG 0.008276pop=5,558
African American C 0.92G 0.08CC 0.848598CG/GC 0.142804GG 0.008598pop=5,350
African Others C 0.99G 0.01CC 0.980769CG/GC 0.019231GG 0pop=208
Asian C 0.807G 0.193CC 0.631579CG/GC 0.350877GG 0.017544pop=114
East Asian C 0.81G 0.19CC 0.636364CG/GC 0.340909GG 0.022727pop=88
European C 0.60319G 0.39681CC 0.359822CG/GC 0.486736GG 0.153442pop=17,114
Latin American 1 C 0.68G 0.32CC 0.482456CG/GC 0.394737GG 0.122807pop=228
Latin American 2 C 0.627G 0.373CC 0.366584CG/GC 0.521197GG 0.112219pop=802
Other C 0.695G 0.305CC 0.496674CG/GC 0.396896GG 0.10643pop=902
Other Asian C 0.81G 0.19CC 0.615385CG/GC 0.384615GG 0pop=26
South Asian C 0.863G 0.137CC 0.72549CG/GC 0.27451GG 0pop=102

Studies10

Unread Studies10
1
Evidence indicates that menarche onset is associated with various health outcomes. Gastroesophageal reflux disease (GERD) is a prevalent condition, which may be …
2
The mesocorticolimbic (MCL) system is crucial in developing risky health behaviors which lead to cardiovascular diseases (CVDs) and type 2 diabetes (T2D). Although there is some …
3
Adolescence is a critical period over ontogenesis. The complex and heterochronous maturation of various brain structures under the influence of several biologically active …
4
The authors draw data from the College Roommate Study (ROOM) and the National Longitudinal Study of Adolescent Health to investigate gene-environment interaction effects on …
5
… Among suicide attempters, rs1451371 and rs1470750 were found to be marginally associated with nonviolent suicide methods. More research is required to corroborate these findings. …
6
… Rs1470750 showed a marginal effect on selfdirectedness (F = 6.36; df = 2,386; p = 0.002) and selftranscendence (F = 5.07; df = 2,386; p = 0.007). Rs998850 was associated with self-…
7
Studies of gene × environment (G × E) interaction in ADHD have previously focused on known risk genes for ADHD and environmentally mediated biological risk. Here we use G × E …
8
… Among suicide attempters, rs1451371 and rs1470750 showed a trend to be associated with … Sliding windows analysis revealed a partial effect of rs1451371 and rs1470750, with the CC …
9
We report here a study considering association of alleles and haplotypes at the DOPA decarboxylase ( DDC ) locus with the DSM-IV diagnosis of nicotine dependence (ND) or a …
10
El suicidio es uno de los problemas de salud pública más importantes a nivel mundial ya que supone entorno al millón de fallecimientos anuales, con …
Curated Studies0

These studies were determined to be useful for this variant — check "Unused Studies" further down if curious what didn't make the cut.

No curated studies yet.

Unused Studies0

No unused studies.