Genetics Research
rs1810126
Population Frequencies12
African
C 0.87163T 0.12837CC 0.762205CT/TC 0.218858TT 0.018937pop=56,082
African American
C 0.86971T 0.13029CC 0.758921CT/TC 0.221572TT 0.019507pop=54,032
African Others
C 0.9224T 0.0776CC 0.84878CT/TC 0.147317TT 0.003902pop=2,050
Asian
C 0.54268T 0.45732CC 0.296899CT/TC 0.491553TT 0.211548pop=15,864
East Asian
C 0.54691T 0.45309CC 0.305068CT/TC 0.483693TT 0.211239pop=11,958
European
C 0.64099T 0.35901CC 0.412082CT/TC 0.457816TT 0.130102pop=517,348
Latin American 1
C 0.6894T 0.3106CC 0.482098CT/TC 0.414701TT 0.103201pop=9,496
Latin American 2
C 0.50146T 0.49854CC 0.255925CT/TC 0.491068TT 0.253006pop=17,130
Other
C 0.64962T 0.35038CC 0.434866CT/TC 0.429513TT 0.135621pop=29,140
Other Asian
C 0.5297T 0.4703CC 0.271889CT/TC 0.515617TT 0.212494pop=3,906
South Asian
C 0.7164T 0.2836CC 0.525488CT/TC 0.381779TT 0.092733pop=3,688
Studies35
Unread Studies35 ▼
1
Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide, with a higher incidence in individuals with diabetes. metformin an antidiabetic drug, has shown …
2
… , CT (rs668871 and rs1810126), is … rs1810126 TT homozygotes have a lower risk of cardiovascular disease [54]. It is worth noting that carriers of the SNVs rs668871/C and rs1810126/T …
3
Congenital anomalies (CA) are common, but the cause is often unknown. The interplay between known environmental teratogens, such as medication use in …
4
The study presents novel machine learning methods aimed at the generalization of subtype identification from national health databases such as the Health and Retirement Study (HRS)…
5
Chronic low back pain (cLBP) is associated with gait impairments. Gait may serve as an important biomarker for improvement following therapy interventions; …
6
GOALS: While disease subtypes are critical for precision medicine, most projects use unipartite clustering methods such as k-means which are not fully automated, do not …
7
… In conclusion, this study provided a new insight into the association between the rs1810126 and rs3088442 SNPs in the SLC22A3 gene and Lp(a). The two SNPs were associated with …
8
… Seven of the variants were significantly associated with small apo(a) isoform size (P=1x10-4 to 2.9x10-18), while rs1810126 and rs3088442 in SLC22A3 were not associated with the …
9
… , rs2048327, rs1810126, and rs3088442 were chosen in our present study for the following reason: while rs2048327 is located in an intron of SLC22A3, rs1810126 and rs3088442 are …
10
Membrane transporters play a pivotal role in maintaining cellular integrity via the removal of toxic metabolites or entry of essential nutrients. Despite regulating cellular influx and efflux, …
11
The current study aimed to investigate the effects of synaptotagmin-like 3 (SYTL3) and solute carrier family 22 member 3 (SLC22A3) single nucleotide polymorphisms (…
12
The current study aims to further delineate the associations between the synaptotagmin-like 3 (SYTL3) and solute carrier family 22 member 3 (SLC22A3) single-nucleotide …
13
… , rs1810126, rs1810126 and rs3088442) are at reduced risk of coronary artery disease development [Citation35–Citation37]. While OCT3 is present in most tissues, the genetic deletion …
14
… Also associated were rs1810126 and rs13192132, two independent modifier variants of the relationship between KIV2-copy number and Lp(a) concentrations [Citation12]. The effect of …
15
… , rs1810126, rs1810126 and rs3088442) are at reduced risk of coronary artery disease development. Similarly, noncoding variants in the UTR contributes to altered metformin …
16
Metabolic deregulation is an emergent hallmark of prostate cancer and studies show that altered patterns of metabolic pathways involved in the development of malignancy. A large …
17
Nos planteamos como objetivo global de esta tesis doctoral investigar mediante estudios experimentales e in silico los cambios en la expresión de las proteínas implicadas en el …
18
Previous a genome‐wide association study (GWAS) of colorectal cancer in Japanese population has identified a risk region at the chromosome 6q26‐q27 associated with colorectal …
19
Prostate cancer (PCa) is the leading cause of new cancer cases and the 3rd most common cause of cancer death among men in the USA. Recent genome-wide association studies (…
20
WGS and baseline characteristics. A total of 8392 participants underwent deep-coverage (mean attained 33× coverage) WGS: 3418 African Americans from the Jackson Heart …
21
Genome-wide association studies (GWAS) enabled us to discover a large number of variants at multiple genomic loci contributing to cardiovascular and metabolic …
22
High variability in clinical response to metformin is often observed in type 2 diabetes (T2D) patients and it highlights the need for identification of genetic components affecting the …
23
High variability in clinical response to metformin is often observed in type 2 diabetes (T2D) patients, and it highlights the need for identification of genetic components …
24
Prostate cancer is the second most common malignancy among men worldwide. Genome-wide association studies have identified 100 risk variants for prostate cancer, which can …
25
The use of antiretroviral therapy (ART) during pregnancy and lactation has significantly reduced the rate of mother-to-child transmission (MTCT) of HIV. However, pregnancy is known to …
26
Genome-wide association studies enabled us to discover a large number of variants and genomic loci contributing to cardiovascular and metabolic disorders. However, …
27
There is great interest in transitioning the antidiabetic drug metformin for use in cancer, with evidence suggesting it can improve outcome following radiotherapy (RT). Its benefit may …
28
Diabetes is a major health problem worldwide, and metformin, a traditional oral anti-hyperglycemic drug, is now believed to be the most widely prescribed antidiabetic drug. Metformin …
29
Nowadays, more and more attentions have been attached to the importance of organic cation transporters (OCTs). OCTs has involved in the transmembrane transport of …
30
有机阳离子转运体(Organic cation transporters, OCTs) 参与许多重要内源性物质和药物的体内 转运过程, 其作用愈来愈被人们所重视. 本文就近年来有关OCTs 与内源性物质和药物的相互…
31
Organic cationic transporter 3 (OCT3, SLS22A3) has only recently emerged as one of the regulators of monoaminergic neurotransmission, which plays a critical role in the pathogenesis …
32
Organic anion transporters (OATs) play an essential role in the disposition of numerous organic anions. To clarify the interindividual variation in the function of OATs, …
33
… For OCT3, interestingly, we identified two variants in the 3-UTR region (rs1810126, rs3088442), linked to one intronic (rs2048327) and in part to one synonymous variant (rs2292334), …
34
… In addition, three noncoding OCT3 variants (rs2048327, rs1810126, and rs3088442) in linkage disequilibrium and one synonymous coding variant (rs2292334) were associated with …
35
博士論文 Page 1 博士論文 ゲノムワイド関連解析による虚血性心疾患の 遺伝的背景に関する研究 松永 紘 Page 2 1 ゲノムワイド関連解析による虚血性心疾患の 遺伝的背景に関する研究 所属:…
Curated Studies0 ▼
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