Genetics Research
rs562
Population Frequencies12
African
T 0.34197C 0.65803TT 0.115982TC/CT 0.451969CC 0.432049pop=61,544
African American
T 0.34361C 0.65639TT 0.117089TC/CT 0.453037CC 0.429875pop=59,408
African Others
T 0.2963C 0.7037TT 0.085206TC/CT 0.422285CC 0.492509pop=2,136
Asian
T 0.4949C 0.5051TT 0.246121TC/CT 0.497557CC 0.256322pop=13,920
East Asian
T 0.50064C 0.49936TT 0.251497TC/CT 0.498276CC 0.250227pop=11,022
European
T 0.514711C 0.485289TT 0.265291TC/CT 0.498839CC 0.23587pop=560,818
Latin American 1
T 0.45448C 0.54552TT 0.206358TC/CT 0.496238CC 0.297404pop=10,632
Latin American 2
T 0.58339C 0.41661TT 0.338803TC/CT 0.489168CC 0.172029pop=18,648
Other
T 0.50394C 0.49606TT 0.25797TC/CT 0.491949CC 0.250081pop=18,506
Other Asian
T 0.4731C 0.5269TT 0.225673TC/CT 0.494824CC 0.279503pop=2,898
South Asian
T 0.5661C 0.4339TT 0.32585TC/CT 0.480444CC 0.193705pop=8,642
Studies51
Unread Studies51 ▼
1
In the GENESECT study, no significant gemcitabine (GEM) metabolism‐related germline genetic polymorphisms (GPs) were identified because approximately 70% of patients …
2
Genetic polymorphisms of molecules are known to cause individual differences in the therapeutic efficacy of anticancer drugs. However, to date, germline mutations (but not …
3
Single nucleotide polymorphisms (SNPs) are changes at specific spots in DNA. These changes help identify genes linked to diseases or trace inherited conditions within families. …
4
Dyslipidemia due to renal insufficiency is a common complication in patients with chronic kidney diseases (CKD), and a major risk factor for the development of cardiovascular events. …
5
Single nucleotide polymorphisms (SNPs) are variations at specific locations in DNA. Sequence responsible for marking genes associated with diseases or tracking inherited diseases …
6
Body surface area (BSA)–based dosing of irinotecan (IR) does not account for its pharmacokinetic (PK) and pharmacodynamic (PD) variabilities. Functional hepatic nuclear …
7
Feeding more people requires an increase in crop productivity. Pulses have an important role in nutritional security across the world. These are enriched sources of protein and are …
8
Irinotecan is an anticancer agent widely used in various solid tumors. Severe neutropenia is one of the most commonly observed toxicities during irinotecan-based chemotherapy …
9
DECLOEDT, Eric H. et al. Pharmacogenetics of tenofovir and emtricitabine penetration into cerebrospinal fluid. South. Afr. j. HIV med.(Online)[online]. 2021, vol. 22, n. 1, pp. 1-24. ISSN …
10
… The aim of this study was to examine whether specific SNPs in genes encoding ABCC5 (rs562; T>C) and ABCC11 (rs17822931; G>A) affect the pharmacokinetics of 5-FU in patients …
11
… For instance, a study on 26 mCRC patients showed that patients with the CC genotype in ABCC5 rs562 or the GG genotype in ABCG1 rs425215 presented higher gastrointestinal …
12
… The consumers’ surplus generated for visitors of domestic origin is estimated at Rs295 billion (US$18.4 billion) and for visitors from the rest of the world is Rs562 billion (US$35 billion). …
13
Irinotecan (CPT-11) is a semisynthetic derivative of the antineoplastic agent camptothecin used in a wide range as an anti-cancer agent in many solid tumors because of its cytotoxic …
14
… The efficacy of 5-FU/capecitabine-based chemotherapy was not related to the polymorphisms rs562, rs1059751, rs2458225, rs3177514, and rs63282661 (data not shown). No …
15
Acute lymphoblastic leukaemia (ALL) has become one of most curable malignancies among all childhood cancers. Such results are possible because of improved understanding of the …
16
This study investigated the impact of ABCB5, ABCC5 and RLIP76 polymorphisms on doxorubicin pharmacokinetics in Asian breast cancer patients (N= 62). Direct sequencing was …
17
Nucleoside drug transporter polymorphisms play a significant role in patient responses to drugs. The aim was to investigate the effect of multi-drug resistance protein 4, multi…
18
In the era of personalized medicine, high-throughput technologies have allowed the investigation of genetic variations underlying the inter-individual variability in drug pharmacokinetics/…
19
… Patients harbouring the ABCC5 rs562 C allele had reduced SN-38G plasma exposure … Decreased plasma levels were observed in patients carrying the ABCC5 rs562 C allele …
20
The patient (germline) genome can influence the pharmacokinetics and pharmacodynamics of cancer therapy. The field of pharmacogenetics (PGx) has primarily focused on genetic …
21
ABCC4, ABCC5 是ABCC (ATP-binding cassette transporter family class C, ABCC) 蛋白转运 体家族的成员, 介导众多内源性代谢产物和外源性药物从细胞内向外转运. ABCC4 和ABCC5 在…
22
… The highest paid CEO happened to draw a salary of Rs562.5 million for the FY2012-13. Despite the slowdown in the economy and the profits of some of these companies were less …
23
Systemic therapeutic efficacy is central to determining the outcome of patients with metastatic colorectal cancer ( CRC ). In these patients, there is a critical need for predictive …
24
Sirolimus is an immunosuppressive medication that acts through inhibition of the Mammalian Target of Rapamycin (MToR) pathway. It is widely used in organ transplantation …
25
Next Generation Sequencing (NGS) technologies have made it possible to assess genetic diversity at an unprecedented pace due to new levels of parallelization which allows for …
26
All arrays passed the quality control metrics (QC> 85%). Alleles that were not in Hardy Weinberg equilibrium were excluded. Duplicate samples revealed high reproducibility …
27
Postęp w dziedzinie informatyzacji instalacji elektrycznych skutkuje powstaniem nowych możliwości w sterowaniu urządzeniami będącymi komponentami systemów automatyki …
28
… In the present study we found that the homozygous C/C genotype in the rs562 SNP which maps in the 3'UTR region of the ABCC5 gene is correlated (p = 0.0022) to grade ≥3 GI toxicity…
29
Recharge patterns, possible flow paths and the relative age of groundwater in the Akaki catchment in central Ethiopia have been investigated using stable environmental isotopes δ 18 …
30
We have developed and validated a consolidated bead-based genotyping platform, the Bioplex suspension array for simultaneous detection of multiple single nucleotide …
31
Das Herz- Kreislaufsystem ist Ziel vielfältiger medikamentöser Interventionen, wobei abhängig von therapeutischer Breite und gewünschtem Effekt des jeweiligen Arzneimittels eine für …
32
MEMS Active Optics Update Page 1 MEMS Active Optics Update William D. Cowan, Olga B. Spahn, Brett E. Bagwell, David V. Wick and Grant D. Grossetete* Sandia is a multiprogram …
33
The multidrug resistance protein 5 (MRP5/ABCC5) has been recently identified as cellular export pump for cyclic nucleotides with 3′,5′-cyclic GMP (cGMP) as a high-affinity substrate…
34
Kaposi's sarcoma-associated herpesvirus (KSHV) epidemiology has not been fully studied in Brazil. This study evaluated the KSHV epidemiology in a well-characterized …
35
This manuscript has been reproduced from the microfilm master. UMI films the text directly from the original or copy …
36
The Idaho Department of Environmental Quality (IDEQ) contracted the Desert Research Institute (DRI) to perform an on-site field study, named the Treasure Valley Road Dust Study (…
37
… (he didn’t mention foe name of foe factory), but after fow months changed hb job and started working as a technical apprentice in a workshop of electrical appliances fora satey of Rs562/…
38
der Strukturanalyse des HSR-Spulensystems Page 1 May-Planck-Institut für Plasmaphysik E. Harmeyer, O. Jandl Anwendung von ANSYS bei der Strukturanalyse des HSR-…
39
Anight-IOng after most visual predators have stopped prowl ing-vampire bats emerge from their roosts and take to the wing, flying low across the landscape in search of warm-blooded …
40
Viola pointed out that last year, course offerings in Open Campus focused on specialized studies." BPI (Business & Professional Institute), non-credit courses, horticulture, computer, …
41
The private automobile has shaped US society to a degree unparalleled by any other prod uct of the industrial age. By providing mobility and convenience particularly attuned to the …
42
While many students cooperated the first day of class, filling 91 percent of lots 9-12 on Thursday, parking on the west side of campus decreased to 48 percent capacity by Monday." The …
43
The best atlas now available in English."-The New lVrk Times. The only atlas printed in 8 colors for clear reading of geographic and political features. This vol ume contains 292 pages …
44
The US is just emerging from the most serious crisis in the his tory of its space program. The suspension of space-shuttle flights after the 1986 Challenger disaster along with concurrent …
45
One hundred years from now the earth may have 10 bil lion inhabitants, about twice as many as it has now. If projec tions made by demographers at the World Bank are correct, the …
46
The yeast IMP1 gene encodes the enzyme thymidylate synthase, which eatalyzes the synthesis of the DNA precursor 'ayataas-monophosphate tare). In this study, the regulatory regions …
47
At BASF, we looked at the problem in a new way. Why not build a production line just for testing paints? The result: a revolutionary, full-scale production line that precisely imitates any of …
48
Gnerally in nature the flow of genetic information is from DNA, where the information resides, to RNA, which serves as an in termediate, to proteins, which are the cell's functional …
49
Supplemental Methods: iPSC. Human induced pluripotent stem cells were maintained at 37 C, 5% CO2, 4% O2 on Matrigel™(BD Biosciences)-coated wells in mTeSR medium (Stem …
50
… Also in this issue we have information on new products from LTC for RS562 serial links. These are reconfigurable RS232/RS562/ RS422/RS485 products that operate in many modes. …
51
Postęp w dziedzinie informatyzacji instalacji elektrycznych skutkuje powstaniem nowych możliwości w sterowaniu urządzeniami będącymi komponentami systemów automatyki …
Curated Studies0 ▼
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