Genetics Research
rs6586282
Population Frequencies12
African
C 0.75762T 0.24238CC 0.57349CT/TC 0.368257TT 0.058253pop=18,574
African American
C 0.75829T 0.24171CC 0.574733CT/TC 0.367104TT 0.058163pop=17,984
African Others
C 0.737T 0.263CC 0.535593CT/TC 0.40339TT 0.061017pop=590
Asian
C 0.993T 0.007CC 0.986027CT/TC 0.013973TT 0pop=8,874
East Asian
C 0.9975T 0.0025CC 0.994951CT/TC 0.005049TT 0pop=7,130
European
C 0.823966T 0.176034CC 0.679317CT/TC 0.289298TT 0.031385pop=238,204
Latin American 1
C 0.8134T 0.1866CC 0.656894CT/TC 0.312995TT 0.030111pop=2,524
Latin American 2
C 0.8607T 0.1393CC 0.738789CT/TC 0.243739TT 0.017472pop=6,868
Other
C 0.8548T 0.1452CC 0.728093CT/TC 0.253319TT 0.018587pop=3,766
Other Asian
C 0.9748T 0.0252CC 0.949541CT/TC 0.050459TT 0pop=1,744
South Asian
C 0.8831T 0.1169CC 0.786003CT/TC 0.194145TT 0.019852pop=5,944
Studies43
Unread Studies43 ▼
1
to analyze the impact of single nucleotide polymorphisms in the genes encoding methylenetetrahydrofolate reductase, methionine synthase, betaine-homocysteine S-…
2
目的探讨抗氧化营养素与妊娠并发症的因果关系, 为妊娠并发症防治提供参考. 方法通过全基因组 关联研究(gwas) 目录和芬兰数据库获得维生素a, 维生素c, 维生素e, 硒, 锌, 铜和铁7 种抗氧化…
3
3. Staley JR, Blackshaw J, Kamat MA, Ellis S, Surendran P, Sun BB, et al. PhenoScanner: a database of human genotype-phenotype associations. Bioinformatics. 2016; 32 (20): 3207-9…
4
The interplay of genetic, immune and environmental factors strongly contributes to the development of autoimmune thyroid disease (AITD), which can be classified as Graves’ disease (…
5
Previous observational studies have discovered a connection between depression and mineral status. Confirming this potential connection is challenging due to …
6
… We also found two SNPs (rs6586282 and rs234709) associated with homocysteine levels. … conducted before and after the removal of rs6586282 and rs234709 were consistent. We …
7
Stroke is currently the second most common cause of death worldwide and a major cause of serious long-term morbidity. Selenium is a trace element with pleotropic effects on human …
8
… In the merge process, the genetically proxied rs7965584 for magnesium and rs6586282 and rs1789953 for selenium were not found in outcome. All the SNPs were robust genetic …
9
Mercury has high industrial utility and is present in many products, and environmental contamination and occupational exposure are widespread. There are numerous biological …
10
The impact of selenium (Se) on human thyroid function remains unclear, with inconsistent results from recent epidemiological studies. Moreover, the observed associations …
11
Mercury has high industrial utility and is present in many products, and environmental contamination and occupational exposure are widespread. There are numerous biological …
12
… We found that rs6586282 was significantly associated with plasma homocysteine levels, … Likewise, excluding the effect of rs6586282 did not significantly change the results of MR …
13
Evidence on the association between selenium and cancer risk is inconclusive. We conducted a Mendelian randomization study to examine the associations of selenium levels with 22 …
14
Frontiers | Genetic association between circulating selenium level and the risk of schizophrenia in the European population: A two-sample Mendelian randomization study Frontiers in …
15
Selenium has been suggested to be protective regarding breast cancer risk but no overall effect has been established. Genetics may modify the effect. This study compares the effect of …
16
Previous results from observational, interventional studies and in vitro experiments suggest that certain micronutrients possess anti-viral and immunomodulatory …
17
The causal relationship between common mineral nutrients and ankylosing spondylitis (AS) has not been studied. So this Mendelian randomization (MR) study aims to …
18
Metal elements have been associated with a wide range of clinical outcomes. The available epidemiological evidence for these associations is often inconsistent …
19
Previous observational studies have shown that there is a controversial association between selenium levels and chronic kidney disease (CKD). Our aim was to assess the …
20
Observational epidemiologic studies have reported a relationship between selenium status and risk for autoimmune diseases. However, the associations are susceptible to …
21
… We also replicated 2 SNPs, rs6859667 on HOMER1 and rs6586282 on CBS, that had reached genomewide significance in a GWAS meta-analysis (9). Among the candidate gene …
22
Pervious epidemiological evidence on the associations of selenium, zinc with lipid profile and glycemic indices was contradictory. The aim of this study was to …
23
Endometrial cancer is the fifth most common cancer diagnosed in women in developed countries. This research used genetics to assess relationships between endometrial cancer and, …
24
Previous research has suggested that the essential nutrient selenium might be protective regarding both risk of, and mortality in, breast cancer. However, the evidence has …
25
Vitamin B12 (Cobalamin) deficiency, due to improper internalization of cobalamin, is a metabolic disorder prevalent in impoverished and elderly populations and is associated …
26
In sports nutrition, the use of genetic information to personalize a nutritional regime seems to be useful to maximize athletic performances. The genetic variability between individuals …
27
… of the rs6586282 polymorphism of … rs6586282 polymorphism of the CBS gene does not alter either tHcy or the effectiveness of folic acid supplementation. The CBS SNP at rs6586282 …
28
… 22763_22793[16_22]) 243 bp downstream of rs6586282 with severe human sepsis. We analyzed the VNTR structure and genotyped variants of rs6586282 and a neighboring SNP (…
29
Obesity is a well‐known risk factor for thrombotic complications. The aim of the present study was to determine the frequency of thrombosis related ABO, F5, MTHFR, and FGG …
30
Selenium (Se) is an essential trace element in human nutrition, but its role in certain health conditions, particularly among Se sufficient populations, is controversial. A genome-wide …
31
Class name: Combinatorial chemistry technology: method, library, apparatus method specially adapted for identifying a library member identifying a library member by means of a tag, …
32
… ENCODE showed that 8 transcription factors (TFs) bound near the rs6031689 SNP, while TRANSFAC predicted that the variant genotype for rs6586282 would bind 4 TFs. EMSA …
33
Genetic variation affecting absorption, distribution or excretion of essential trace elements may lead to health effects related to sub-clinical deficiency. We have tested for allelic effects of …
34
Cardiovascular disease (CVD) is the leading cause of illness and death worldwide with an estimated annual one million deaths occurring in the United States alone. Biomarkers of …
35
… alleles among three SNPs (rs12329764, rs6586282, and rs1051319) for white subjects … We found three SNPs (rs12329764, rs6586282, and rs1005584) with significantly higher …
36
The Vitamin Intervention for Stroke Prevention trial found an association between baseline poststroke homocysteine (Hcy) and recurrent stroke. We investigated genes for …
37
… rs6586282 CBS 21 43 351 566 A 0.18 −0.030 ± 0.005 3.2 × 10 −10 — — … CBS SNP rs6586282 was neither genotyped nor … CBS SNP rs6586282 was neither genotyped nor successfully …
38
Cardiac abnormalities are one of the most common congenital defects observed in individuals with Down syndrome. Considerable research has implicated both folate deficiency and …
39
… Although genetic variants of CBS have previously been reported to influence homocysteine concentration, 11,12 the intronic CBS SNP rs6586282 described in this report is either in …
40
Total plasma homocysteine concentration (tHcy) is a biomarker for atherothrombotic disease, but causality remains uncertain. Polymorphisms in the genes involved in methionine …
41
HUMAN GENETICS Page 1 THE GENETICS AND EPIDEMIOLOGY OF REPRODUCTIVE DISORDERS By Kelli Ryckman Dissertation Submitted to the Faculty of the Graduate School …
42
Spontaneous preterm birth (<37 weeks gestation—PTB) occurs in ∼12% of pregnancies in the United States, and is the largest contributor to neonatal morbidity and mortality. PTB is a …
43
… U drugoj velikoj studiji, u kojoj je analizirano 336469 polimorfizama u 13974 zdravih žena bijele rase, utvrđena je povezanost polimorfizama MTHFR (rs1801133) i CBS (rs6586282) s …
Curated Studies0 ▼
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