Genetics Genetics Research
CHROMOSOME 16 GRIN2A 16p13.2 GENE VIEW GRIN2A · 16p13.2 16p14 16p12 rs7203315 — ~70,000 base pairs in the gene — ~14,000 uncommon variants · <1% of humans have them — ~1,000 common variants · >1% carry the alternate allele ALLELE STATE rs7203315 G / A · GRIN2A · 16p13.2 HOMOZYGOUS WILD TYPE (DOMINANT) 5′ 3′ G 5′ 3′ G HETEROZYGOUS 5′ 3′ G 5′ 3′ A HOMOZYGOUS ALTERNATE (RECESSIVE) 5′ 3′ A 5′ 3′ A G Guanine — reference allele A Adenine — variant allele genetics.jdge.cc

rs7203315

Gene: GRIN2A — Glutamate Ionotropic Receptor NMDA Type Subunit 2A Chr 16:10094203 16p13.2
NCBI ↗ GeneCards ↗ Open Targets ↗ gnomAD ↗ OMIM ↗ Varsome ↗ LOVD ↗

Population Frequencies12

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Total G 0.855269T 0.144731GG 0.73428GT/TG 0.241978TT 0.023742pop=491,202 ↬
African G 0.71866T 0.28134GG 0.516455GT/TG 0.404418TT 0.079127pop=53,054
African American G 0.72011T 0.27989GG 0.518597GT/TG 0.403032TT 0.078372pop=51,192
African Others G 0.6788T 0.3212GG 0.457573GT/TG 0.442535TT 0.099893pop=1,862
Asian G 0.9321T 0.0679GG 0.869505GT/TG 0.125242TT 0.005253pop=7,234
East Asian G 0.9267T 0.0733GG 0.859549GT/TG 0.134389TT 0.006063pop=5,938
European G 0.869514T 0.130486GG 0.756314GT/TG 0.2264TT 0.017285pop=387,146
Latin American 1 G 0.8344T 0.1656GG 0.697656GT/TG 0.2735TT 0.028844pop=7,766
Latin American 2 G 0.92163T 0.07837GG 0.850798GT/TG 0.141669TT 0.007533pop=17,788
Other G 0.86383T 0.13617GG 0.748981GT/TG 0.229696TT 0.021323pop=12,756
Other Asian G 0.9568T 0.0432GG 0.915123GT/TG 0.083333TT 0.001543pop=1,296
South Asian G 0.8642T 0.1358GG 0.747527GT/TG 0.233419TT 0.019055pop=5,458

Studies1

Unread Studies1 ▼
1

Genetic Predictors Of Metabolic Side Effects Of Diuretic Therapy

Study ↗ PDF ↗
Thiazide diuretics are a recommended first-line monotherapy for hypertension (ie SBP> 140 mmHg or DBP> 90 mmHg). Even so, diuretics are associated with adverse metabolic side …

2014 · JL Del Aguila

Curated Studies0 ▼

These studies were determined to be useful for this variant — check "Unused Studies" further down if curious what didn't make the cut.

No curated studies yet.

Unused Studies0 ▼

No unused studies.