Genetics Research
rs769224
Population Frequencies12
African
G 0.90991A 0.09009GG 0.827867GA/AG 0.164077AA 0.008055pop=62,568
African American
G 0.91075A 0.08925GG 0.829537GA/AG 0.162418AA 0.008045pop=60,412
African Others
G 0.8864A 0.1136GG 0.781076GA/AG 0.210575AA 0.008349pop=2,156
Asian
G 0.95104A 0.04896GG 0.903747GA/AG 0.094578AA 0.001675pop=13,132
East Asian
G 0.94802A 0.05198GG 0.898161GA/AG 0.09971AA 0.00213pop=10,330
European
G 0.978374A 0.021626GG 0.957217GA/AG 0.042313AA 0.00047pop=523,758
Latin American 1
G 0.956A 0.044GG 0.914305GA/AG 0.083464AA 0.002232pop=8,962
Latin American 2
G 0.97695A 0.02305GG 0.954307GA/AG 0.045279AA 0.000414pop=14,488
Other
G 0.96916A 0.03084GG 0.939984GA/AG 0.058351AA 0.001665pop=27,626
Other Asian
G 0.9622A 0.0378GG 0.92434GA/AG 0.07566AA 0pop=2,802
South Asian
G 0.9797A 0.0203GG 0.960422GA/AG 0.038522AA 0.001055pop=3,790
Studies37
Unread Studies37 ▼
1
The main causes of early mortality in patients with schizophrenia are comorbid somatic diseases (primarily cardiovascular diseases, diabetes, and obesity) and suicide, which reduces …
2
Major depressive disorder (MDD) is a prevalent and debilitating psychiatric condition defined by complex genetic and neurobiological underpinnings. The current study …
3
… study found that individuals carrying the C allele of ADRA1A rs3808585 are more susceptible to memory impairment after heroin use and subjects with G allele of COMT rs769224 are …
4
Catechol-O-methyltransferase (COMT) is one of the cardinal enzymes in the degradation of catecholamines and levodopa. Genetic variants of the COMT gene may affect COMT enzyme …
5
A new concept of empathy was adopted in this study to elucidate the relationship between empathy and age and eight catechol-O-methyltransferase (COMT) gene polymorphisms. One …
6
A previous exploratory analysis of a COMT gene single-nucleotide polymorphism (SNP) and a DRD3 SNP by our group suggested possible contributions to pain-related acute care …
7
… Subjects with the G allele of COMT rs769224 were more likely to take a higher dose of heroin every day. Our study confirmed the association between polymorphisms of COMT and …
8
… The findings of the study suggested that subjects having the G (guanine) allele of rs769224 COMT variant were prone to consuming higher dosages of heroin every day and concluded …
9
… Similarly, our primary study failed to identify an association of missense SNP rs4680, synonymous SNP rs4633 and rs769224 with susceptibility to PD, but a larger sample size is …
10
Hyperprolactinemia (HPRL) is considered to be a frequent and typical adverse drug reaction caused by antipsychotic medications first and foremost due to excessive dopamine D2 …
11
The present study systematically investigated if genetic variations in the DRD2 and COMT interacted with parenting style to predict individual differences in creativity. In a sample of …
12
ФАРМАКОГЕНЕТИКА ГИПЕРПРОЛАКТИНЕМИИ: ФОКУС НА ФАРМАКОКИНЕТИЧЕСКИЕ И ФАРМАКОДИНАМИЧЕСКИЕ ГЕНЫ Page 67 Тезисы докладов Российской …
13
Новые подходы к фармакогенетике лекарственно-индуцированной гиперпролактинемии у больных шизофренией
Патогенез развития лекарственно- индуцированных расстройств на фоне приема антипсихотических средств изучен недостаточно. Целью работы является изучение …
14
… 199Pro (rs769224).Xu et al demonstrated an association of the G–G–G vs. A–G–G haplotype of rs4633, rs4818 and rs769224 concerning response to non-SSRIs in major depressive …
15
To investigate whether there is an association between gene polymorphisms, genetic and environmental interactions, and psychological stress reactivity in Chinese subjects living in …
16
Alcohol use disorder (AUD) is a chronic relapsing brain disease characterized by compulsive alcohol use, loss of control over alcohol intake, and a negative emotional …
17
Полиморфный вариант rs165774 гена катехол-О-метилтрансферазы, фермента метаболизма дофамина, вносит вклад в развитие гиперпролактинемии у пациентов с …
18
Parkinson's disease (PD) is one of the most serious and widespread neurodegenerative diseases. Genetic susceptibility plays a significant role in the development of PD. The aim of our …
19
Болезнь Паркинсона одно из наиболее тяжелых и распространенных нейродегенеративных заболеваний. Подавляющее большинство случаев заболевания представлено …
20
Parkinson's disease (PD) is one of the most serious and widespread neurodegenerative disorders. Genetic susceptibility plays a significant role in the development of PD. …
21
Alcohol use disorders (AUD)–a tremendous issue in modern society, which affects nearly all the countries in the modern world. Lithuania–a leading country, according to pure …
22
Autism spectrum disorders (ASD) are related to serotonin transporter (5‐HTT) and catechol‐O‐methyl transferase (COMT) as two most monoaminergic polymorphic variations. However, …
23
Parkinson's disease (PD), a common neurodegenerative disorder caused by the loss of the dopaminergic input to the basal ganglia, is commonly treated with levodopa (L-DOPA). Use …
24
Otizm Spektrum Bozukluğu, yaşamın ilk üç yılı içinde ortaya çıkan, sosyal ilişkilerde ve iletişimde problemler, tekrarlayıcı davranış ve kısıtlı ilgi alanlarıyla karakterize olup, yaşam boyu …
25
… -rs174675-rs5993882) were nominally associated with figural originality, and the TATGCAG and CGCGGGA haplotype (rs4646312-rs6269-rs4633-rs6267-rs4818-rs4680-rs769224) …
26
This study evaluated the family-based genetic association between autism spectrum disorders (ASDs) and 5 single-nucleotide polymorphisms (SNPs) in the catechol-o-…
27
Previously, we reviewed biological evidence that mercury could induce autoimmunity and coronary arterial wall relaxation as observed in Kawasaki syndrome (KS) through its effects on …
28
… Two haplotypes in COMT (involving rs4633, rs4818 and rs769224) were significantly associated with antidepressant response in the nonSSRI subgroup. The SLC6A2 SNPs interacted …
29
… Analysis with the Haploview program showed that SNPs rs6267, rs4818 and rs4680 were in the same LD block, but rs4633 and rs769224 were in the upstream and downstream of the …
30
… We have confirmed that for one SNP (SNP 21), rs769224, the allelic states differ in chimpanzee and gorilla. We infer from haplotype evidence that the gorilla allele is the ancestral allele …
31
The human catechol-O-methyl transferase (COMT) gene contains multiple single-nucleotide polymorphisms, some of which are postulated to have clinical significance. This article …
32
… Computer analysis of COMT ESTs showed that one synonymous minor SNP (rs769224) is linked to the APS haplotype and three minor SNPs (two synonymous: rs6267, rs740602 and …
33
… Computer analysis of COMT ESTs showed that one synonymous minor SNP (rs769224) is linked to the APS haplotype and three minor SNPs (two synonymous: rs6267, rs740602 and …
34
… of the rs4680 and rs769224 polymorphic sites between … However, the distribution of the rs769224 polymorphism was … the polymorphisms of the rs769224 gene might be related to …
35
… of the rs4680 and rs769224 polymorphic sites between … However, the distribution of the rs769224 polymorphism was … the polymorphisms of the rs769224 gene might be related to …
36
… The results for the two minor synonymous SNPs assessed in this study suggest that rs769224 and rs740602 have a neutral effect on RNA abundance, protein expression, and …
37
Stan przedrzucawkowy (PE–preeclampsia) jest poważnym i złożonym powikłaniem ciąży. Częstość występowania tego schorzenia szacuje się na 5-8% ciężarnych na świecie. PE …
Curated Studies0 ▼
These studies were determined to be useful for this variant — check "Unused Studies" further down if curious what didn't make the cut.
No curated studies yet.
Unused Studies0 ▼
No unused studies.